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- URN to cite this document:
- urn:nbn:de:bvb:355-opus-5332
- DOI to cite this document:
- 10.5283/epub.10327
Abstract (German)
Der Kontakt zwischen Melanozyten und Keratinozyten ist von enormer Bedeutung für die Aufrechterhaltung des geordneten Gewebeverbands der menschlichen Epidermis. Keratinozyten regulieren durch das Zell-Zell-Adhäsionsmolekül E-cadherin die Morphologie und die Proliferation von Melanozyten. Ein Verlust der E-Cadherin Expression und Neuexpression von N-Cadherin in entarteten Melanozyten konnte ...

Translation of the abstract (English)
Crosstalk between melanocytes and keratinocytes is important in the human epidermis. It is known that the normal melanocytic phenotype and controlled proliferation of melanocytes is strictly regulated by keratinocytes via E-cadherin. Malignant transformation of melanocytes frequently coincides with loss of E-cadherin expression and the upregulation of N-cadherin. This leads to the loss of ...
