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Identification and functional characterization of a mouse lymphotoxin beta-receptor like protein

Seegers, Silvia (2005) Identification and functional characterization of a mouse lymphotoxin beta-receptor like protein. Masters, Universität Regensburg.

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Date of publication of this fulltext: 15 Nov 2005 07:03

Abstract (English)

Four different monoclonal rat anti mouse lymphotoxin beta-receptor (mLTbetaR) antibodies were generated in order to study the expression patterns and molecular mechanisms that follow the activation of this receptor which belongs to the TNFR superfamily. One of these four antibodies, namely 1C5, cross-reacts with a protein on thymocytes of wildtype and LTbetaR-/- mice. Since thymocytes do not ...


Translation of the abstract (German)

Für die Untersuchungen des Expressionsmusters und der molekularen Mechanismen, die der Aktivierung des Maus Lymphotoxin beta-Rezeptor (mLTbetaR) folgen, wurden vier unterschiedliche monoklonale Ratten-Antikörper gegen diesen Rezeptor, einem Mitglied der TNFR-Superfamilie, hergestellt. Einer dieser Antikörper, 1C5, kreuzreagiert mit einem Protein auf Thymozyten von Wildtyp-Mäusen und ...


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Item type:Thesis of the University of Regensburg (Masters)
Date:14 November 2005
Referee:Prof. Adrian Hayday
Date of exam:16 May 2005
Institutions:Medicine > Lehrstuhl für Immunologie
Medicine > Lehrstuhl für Pathologie
Keywords:Lymphotoxin , Beta-Rezeptor , , Lymphotoxin beta-receptor , thymocyte differentiation , activated T- and B-cells , epitope mapping , TNFR superfamily
Dewey Decimal Classification:500 Science > 570 Life sciences
600 Technology > 610 Medical sciences Medicine
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:10357
Owner only: item control page


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