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New approaches to the chemotherapy of glioblastoma: investigations on doxorubicin nanoparticles, inhibition of PDGF receptors and kinesin Eg5, with emphasis on confocal laser-scanning microscopy

Gross, Dietmar (2006) New approaches to the chemotherapy of glioblastoma: investigations on doxorubicin nanoparticles, inhibition of PDGF receptors and kinesin Eg5, with emphasis on confocal laser-scanning microscopy. PhD, Universität Regensburg.

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Date of publication of this fulltext: 18 Sep 2006 07:51

Abstract (English)

The treatment of malignant brain tumors poses a basic challenge in todays cancer therapy. Since the quantitative resection is hardly possible due to the invasive growth of the tumor, prevention of relapse after resection by concomitant irradiation treatment and chemotherapy is of major importance for patient outcome. While surgery and irradiation therapy seem to be exploited, new approaches in ...

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Translation of the abstract (German)

Die Therapie maligner Hirntumore stellt eine grundlegende Herausforderung in der heutigen Krebstherapie dar. Die Prävention von Rezidiven mittels Strahlen- und Chemotherapie nach operativer Tumorentfernung ist von entscheidender Bedeutung für das Patientenüberleben. Da die Grenzen der Effektivität von Chirurgie und Strahlentherapie derzeit erreicht sind, liegen die Zukunftshoffnungen in neuen ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:17 September 2006
Referee:Prof. Dr. Armin Buschauer
Date of exam:24 August 2006
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer)
Keywords:Glioblastom , Doxorubicin , Nanopartikel , Platelet-derived Growth Factor , Rezeptor , Kinesin , Chemotherapie , Doxorubicin-Nanopartikel , PDGF Rezeptor , Kinesin Eg5 , glioblastoma , doxorubicin , nanoparticles , PDGF receptor , kinesin Eg5
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:10466
Owner only: item control page

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