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New approaches to the chemotherapy of glioblastoma: investigations on doxorubicin nanoparticles, inhibition of PDGF receptors and kinesin Eg5, with emphasis on confocal laser-scanning microscopy

URN to cite this document:
urn:nbn:de:bvb:355-opus-7074
Gross, Dietmar
Date of publication of this fulltext: 18 Sep 2006 07:51


Abstract (English)

The treatment of malignant brain tumors poses a basic challenge in todays cancer therapy. Since the quantitative resection is hardly possible due to the invasive growth of the tumor, prevention of relapse after resection by concomitant irradiation treatment and chemotherapy is of major importance for patient outcome. While surgery and irradiation therapy seem to be exploited, new approaches in ...

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Translation of the abstract (German)

Die Therapie maligner Hirntumore stellt eine grundlegende Herausforderung in der heutigen Krebstherapie dar. Die Prävention von Rezidiven mittels Strahlen- und Chemotherapie nach operativer Tumorentfernung ist von entscheidender Bedeutung für das Patientenüberleben. Da die Grenzen der Effektivität von Chirurgie und Strahlentherapie derzeit erreicht sind, liegen die Zukunftshoffnungen in neuen ...

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