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Drug delivery to the bone-implant interface: Functional hydroxyapatite surfaces and particles

URN to cite this document:
urn:nbn:de:bvb:355-opus-7416
Schüssele, Andrea
Date of publication of this fulltext: 10 May 2007 08:12


Abstract (English)

With the goal of controlling the events at the bone-implant interface, it was the main objective of this thesis to provide a basis for the conjugation of cell stimulating molecules or targeting motifs to the surface of hydroxyapatite ceramic discs and particles. To this end, methods for surface functionalization have been investigated for the attachment of biomolecules. The approach focused on ...

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Translation of the abstract (German)

Um die Ereignisse an der Grenzfläche Knochen-Implantat zu kontrollieren, war es das Hauptziel dieser Arbeit, eine Basis für die Anbindung von zellstimulierenden Molekülen oder Targetingsequenzen an die Oberfläche von Hydroxylapatit-Keramikscheiben und Partikeln zu schaffen. Der gewählte Ansatz konzentrierte sich darauf, drei verlässliche und effiziente Prinzipien für die gesteigerte ...

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