Schüssele, Andrea (2007) Drug delivery to the bone-implant interface: Functional hydroxyapatite surfaces and particles. PhD, Universität Regensburg.
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Abstract (English)
With the goal of controlling the events at the bone-implant interface, it was the main objective of this thesis to provide a basis for the conjugation of cell stimulating molecules or targeting motifs to the surface of hydroxyapatite ceramic discs and particles. To this end, methods for surface functionalization have been investigated for the attachment of biomolecules. The approach focused on ...

Translation of the abstract (German)
Um die Ereignisse an der Grenzfläche Knochen-Implantat zu kontrollieren, war es das Hauptziel dieser Arbeit, eine Basis für die Anbindung von zellstimulierenden Molekülen oder Targetingsequenzen an die Oberfläche von Hydroxylapatit-Keramikscheiben und Partikeln zu schaffen. Der gewählte Ansatz konzentrierte sich darauf, drei verlässliche und effiziente Prinzipien für die gesteigerte ...

Export bibliographical data
Item type: | Thesis of the University of Regensburg (PhD) |
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Date: | 9 May 2007 |
Referee: | Achim (Prof. Dr.) Göpferich |
Date of exam: | 2 November 2006 |
Institutions: | Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical Technology (Prof. Göpferich) |
Keywords: | Hydroxylapatit , Knochen-Morphogenese-Proteine , Keramischer Werkstoff , Diphosphonate , Immobilisierung , Oberflächenmodifizierung , surface modification , bone morphogenetic protein , hydroxyapatite , ceramic , bisphosphonates |
Dewey Decimal Classification: | 600 Technology > 610 Medical sciences Medicine |
Status: | Published |
Refereed: | Yes, this version has been refereed |
Created at the University of Regensburg: | Yes |
Item ID: | 10511 |