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Molekulare Mechanismen der Hepatokanzerogenese

Amann, Thomas (2008) Molekulare Mechanismen der Hepatokanzerogenese. PhD, Universität Regensburg.

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Date of publication of this fulltext: 09 Apr 2008 16:23

Abstract (German)

Das hepatozelluläre Karzinom (HCC) ist einer der häufigsten malignen Tumoren weltweit mit weiterhin steigender Inzidenz. Die Prognose des HCC ist außerordentlich schlecht, da bisher keine effektiven Therapieansätze existieren und das Tumorstadium zum Zeitpunkt der Diagnose meist schon weit fortgeschritten ist. Die Leberzirrhose stellt den Hauptrisikofaktor für die HCC-Entstehung dar. Diese ...

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Translation of the abstract (English)

Hepatocellular carcinoma (HCC) is one of the most malignant tumors worldwide with an increasing incidence. Since there is a lack of effective therapeutic strategies and the majority of patients is diagnosed at an advanced stage the HCC prognosis remains poor. The presence of liver cirrhosis is the main risk factor for the development of HCC. Activated hepatic stellate cells (HSC) are the ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:8 April 2008
Referee:Rainer (Prof. Dr.) Deutzmann
Date of exam:27 February 2008
Institutions:Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Biochemie I > Prof. Dr. Rainer Deutzmann
Keywords:Kupffer-Sternzelle , Stroma , Leberzellkrebs , Carcinogenese , Glucosetransportproteine , Genregulation , Protein MIA , Fibroblastenwachstumsfaktor , HCC , aktivierte hepatische Sternzelle , Hepatokanzerogenese , Leberkarzinom , Tumorstroma , liver , cirrhosis , fibrosis , hepatocancerogenesis , activated hepatic stellate cell
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:10728
Owner only: item control page

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