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Site-specific phosphorylation of yeast RNA polymerase I

URN to cite this document:
urn:nbn:de:bvb:355-opus-9666
Gerber, Jochen
Date of publication of this fulltext: 06 May 2008 16:24


Abstract (English)

A tight control of ribosome biogenesis in dependence of the growth conditions is crucial for the economics of a cell. Signal transduction cascades forward the status of environmental factors to several key regulatory steps via reversible phosphorylation. As one of the first steps of ribosome biogenesis, the transcription of the 35S rRNA precursor by RNA polymerase I (Pol I) is also one of the ...

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Translation of the abstract (German)

Eine strikte Kontrolle der Ribosomen Biogenese in Abhängigkeit der Wachstumsbedingungen ist entscheidend für den Energiehaushalt einer Zelle. Signal-Transduktions-Kaskaden übermitteln die Umweltbedingungen an mehrere Schlüsselstellen mittels reversibler Phosphorylierung. Die Transkription der 35S Vorläufer rRNA durch die RNA Polymerase I (Pol I) ist, als einer der ersten Schritte der Ribosomen ...

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