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Establishment of functional cannabinoid receptor test systems and evaluation of ligands derived from Echinacea pallida

URN to cite this document:
urn:nbn:de:bvb:355-opus-9892
Nickl, Kathrin
Date of publication of this fulltext: 18 Jun 2008 16:25


Abstract (English)

Cannabinoid receptors (CBRs) have been of high interest since their discovery in the early 1990s. Until now, two different subtypes, the human cannabinoid receptor 1 (hCB1R) and the human cannabinoid receptor 2 (hCB2R) are known. Both regulate important body functions, such as appetite, motor coordination, inflammation and host defence. Identifying new ligands at CBRs is of high importance for ...

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Translation of the abstract (German)

Seit ihrer Entdeckung in den frühen 1990er Jahren war das wissenschaftliche Interesse an Cannabinoid-Rezeptoren (CBR) groß. Zur Zeit sind zwei verschiedene Subtypen, der humane Cannabinoid-Rezeptor 1 (hCB1R) und der humane Cannabinoid-Rezeptor 2 (hCB2R) bekannt. Beide Rezeptoren regulieren wichtige Körperfunktionen, z. B. Appetit, Motorik, Entzündungen und Immunabwehr. CBR-Liganden sind als ...

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