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The genome sequence of Clostridium tetani, the causative agent of tetanus disease

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Brüggemann, Holger ; Baumer, Sebastian ; Fricke, Wolfgang Florian ; Wiezer, Arnim ; Liesegang, Heiko ; Decker, Ivona ; Herzberg, Christina ; Martinez-Arias, Rosa ; Merkl, Rainer ; Henne, Anke ; Gottschalk, Gerhard
Date of publication of this fulltext: 18 Nov 2009 09:02


Abstract: Tetanus disease is one of the most dramatic and globally prevalent diseases of humans and vertebrate animals, and has been reported for over 24 centuries. The manifestation of the disease, spastic paralysis, is caused by the second most poisonous substance known, the tetanus toxin, with a human lethal dose of approximate to1 ng/kg. Fortunately, this disease is successfully controlled ...


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