Monoclonal antibodies against contact sites A of Dictyostelium discoideum: detection of modifications of the glycoprotein in tunicamycin-treated cells

URN to cite this document:: urn:nbn:de:bvb:355-epub-109322
DOI to cite this document:: 10.5283/epub.10932

Ochiai, H. ; Stadler, J. ; Westphal, M. ; Wagle, G. ; Merkl, Rainer ; Gerisch, G.

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Date of publication of this fulltext: 16 Nov 2009 08:15

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Abstract

Tunicamycin acts on cell aggregation in Dictyostelium discoideum by changing cell movement and by inhibiting the EDTA-stable type of intercellular adhesion. Tunicamycin-treated cells show unco-ordinated pseudopodial activity such that pseudopods are simultaneously extended from all parts of the cell surface, and the cells are unable to move in straight paths. Concurrent with the inhibition of ...