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P-3-[2-(4-hydroxyphenyl)-2-oxo]ethyl ATP for the rapid activation of the Na+,K+-ATPase

Geibel, S. ; Barth, A. ; Amslinger, S. ; Jung, A. H. ; Burzik, C. ; Clarke, R. J. ; Givens, R. S. ; Fendler, K.


P-3-[2-(4-hydroxyphenyl)-2-oxo]ethyl ATP (pHP-caged ATP) has been investigated for its application as a phototrigger for the rapid activation of electrogenic ion pumps. The yield of ATP after irradiation with a XeCl excimer laser (lambda = 308 nm) was determined at pH 6.0-7.5. For comparison, the photolytic yields of P-3-[1-(2-nitrophenyl)]ethyl ATP (NPE-caged ATP) and ...


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