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Localization of proliferating cell nuclear antigen, vimentin, c-Fos, and clusterin in the postischemic kidney. Evidence for a heterogenous genetic response among nephron segments, and a large pool of mitotically active and dedifferentiated cells

URN to cite this document:
urn:nbn:de:bvb:355-epub-112088
Witzgall, Ralph ; Brown, Dennis ; Schwarz, Cordula ; Bonventre, Joseph V.
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Date of publication of this fulltext: 06 Dec 2010 09:18


Abstract

The mechanisms leading to the recovery of the kidney after ischemic acute renal failure are poorly understood. To explore the role played by mitogenesis and dedifferentiation in this repair process and to identify whether the genetic response of the nephron segments reflects the level of susceptibility to injury, the temporal and nephron segment expressions of various proteins implicated in ...

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