Rosai-Dorfman disease with cutaneous manifestation (sinus histiocytosis with massive lymphadenopathy)

Zusammenfassung

We report a 73-year-old woman with the typical findings of "Rosai-Dorfman disease" (RDD) including massive, painless lymphadenopathy, fever and multiple, asymptomatic cutaneous lesions on her face, collum and neck. Histologically, the lesions were marked by characteristic large macrophages exhibiting emperipolesis.