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Function of the upstream activating factor in chromatin structure organization and transcriptional regulation at the yeast ribosomal DNA

Götze, Hannah (2010) Function of the upstream activating factor in chromatin structure organization and transcriptional regulation at the yeast ribosomal DNA. PhD, Universität Regensburg.

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Date of publication of this fulltext: 20 Apr 2010 11:25

Abstract (English)

Chromatin is the template of all processes involved in DNA metabolism in the eukaryotic cell. Accordingly, chromatin is a dynamic structure which changes in its composition and posttranslational modification correlating with the functional state of a genomic locus. An excellent example to study the correlation between transcription and chromatin structure is the ribosomal DNA (rDNA) locus in ...

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Translation of the abstract (German)

Der Upstream Activating Factor UAF spielt eine wichtige Rolle bei der Regulation der Transkription der ribosomalen RNA Gene durch Polymerase I in S. cerevisiae. UAF ist ein Multiproteinkomplex bestehend aus den 6 Untereinheiten Rrn5, Rrn9, Rrn10, Uaf30, und den Histonen H3 und H4. Die Bindung von UAF an den rDNA Promotor stimuliert die Transkription der rRNA Gene. Gleichzeitig determiniert UAF ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:20 April 2010
Referee:Prof. Dr. Herbert Tschochner
Date of exam:25 January 2010
Institutions:Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Biochemie III > Prof. Dr. Herbert Tschochner
Keywords:UAF, rDNA, chromatin, S. cerevisiae
Dewey Decimal Classification:500 Science > 570 Life sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:12558
Owner only: item control page

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