Modulation of HIV-1 enhancer activity and virus production by cAMP

DOI zum Zitieren dieses Dokuments:: 10.5283/epub.1265

Banas, B. ; Eberle, J. ; Banas, B. ; Schlöndorff, D. ; Luckow, B.

PDF
(207kB) - Nur für Mitarbeiter des Archivs

Veröffentlichungsdatum dieses Volltextes: 05 Aug 2009 13:26

Alternative Links zum Volltext:Pubmed

Details

Bibliographische Daten exportieren

Zusammenfassung

The effect of cAMP on the transcriptional activity of the HIV-1 long terminal repeat/enhancer was investigated and compared to the effect of cAMP on virus replication. In culture cAMP repressed virus replication in vivo using different cell types. Transient transfection studies with HIV-1 enhancer-derived luciferase reporter gene constructs identified the minimal DNA sequence mediating the ...