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Novel role of toll-like receptor 3 in hepatitis C-associated glomerulonephritis

Wörnle, Markus, Schmid, Holger, Banas, Bernhard, Merkle, Monika, Henger, Anna, Roeder, Maximilian, Blattner, Simone, Bock, Elisabeth, Kretzler, Matthias, Gröne, Hermann-Josef and Schlöndorff, Detlef (2006) Novel role of toll-like receptor 3 in hepatitis C-associated glomerulonephritis. The American journal of pathology 168 (2), pp. 370-385.

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Date of publication of this fulltext: 05 Aug 2009 13:27

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Other URL: DOI:10.2353/ajpath.2006.050491


Hepatitis C virus (HCV) infection is frequently complicated by glomerulonephritis with immune complexes containing viral RNA. We examined the potential influence of Toll-like receptors (TLRs), specifically TLR3 recognition of viral dsRNA exemplified by polyriboinosinic:polyribocytidylic acid [poly(I:C) RNA]. Normal human kidney stained positive for TLR3 on mesangial cells (MCs), vascular smooth ...


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Item type:Article
Date:February 2006
Institutions:Medicine > Lehrstuhl für Innere Medizin II
Identification Number:
16436653PubMed ID
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:1311
Owner only: item control page


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