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Untersuchung der Fluoreszenz- und Elektronentransfereigenschaften von Phenanthridinium-Derivaten in DNA

Prunkl, Christa (2010) Untersuchung der Fluoreszenz- und Elektronentransfereigenschaften von Phenanthridinium-Derivaten in DNA. PhD, Universität Regensburg.

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Date of publication of this fulltext: 18 Mar 2010 11:13

Abstract (German)

Ethidiumbromid (E) wird aufgrund seines starken Fluoreszenzanstiegs bei Interkalation in DNA seit Jahrzehnten zum Anfärben von Oligonukleotiden verwendet. Trotz intensiver Bemühungen ist die Ursache dieser Intensitätserhöhung bislang nicht komplett verstanden und kann mit keinem der vorgeschlagenen Modelle vollständig erklärt werden. Um neue Erkenntnisse bezüglich der Gründe des starken ...

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Translation of the abstract (English)

Due to its significant emission increase upon binding to DNA ethidiumbromide (E) was widely used as fluorescent staining agent for decades. Understanding the unique intercalation and emission properties of E had been the aim of a number of intense studies. However, up to now none of the postulated models is capable to explain all results. In order to obtain new insights concerning the ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:18 March 2010
Referee:Prof. Dr. Hans-Achim Wagenknecht
Date of exam:29 January 2010
Institutions:Chemistry and Pharmacy > Institut für Organische Chemie > Alumni or Retired Professors > Arbeitskreis Prof. Dr. Hans-Achim Wagenknecht
Keywords:Ladungstransfer, Ethidium, Phenanthridinium Farbstoffe, DNA, Interkalation, charge transfer, phenanthridinium chromophores, intercalation, Methylviologen
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:13163
Owner only: item control page

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