Induction of human monocyte to macrophage maturation in vitro by 1,25-dihydroxyvitamin D3

URN to cite this document:: urn:nbn:de:bvb:355-epub-142576
DOI to cite this document:: 10.5283/epub.14257

Kreutz, Marina ; Andreesen, Reinhard

Preview

PDF
(1MB)

Date of publication of this fulltext: 14 Apr 2010 05:36

Alternative links to fulltext:Pubmed

Details

Preview

Export bibliographical data

Abstract

Cells of the mononuclear phagocyte system arise from circulating blood monocytes (MO) that undergo further maturation on leaving the vasculature and migration into the various tissues and body cavities. This terminal differentiation step is also observed in vitro when blood MO are cultured in the presence of serum. Yet, the inducing signals present in serum are not defined. We have established ...