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A new approach to adoptive immunotherapy of cancer using tumorcytotoxic macrophages grown from peripheral blood monocytes

Andreesen, Reinhard ; Scheibenbogen, C. ; Brugger, W. ; Krause, S. ; Leser, H. G. ; Kopf, S. ; Engler, H. ; Schümichen, C. ; Löhr, G. W.


Clinical trials to evaluate the potential of adoptive immunotherapy in cancer patients have been restricted to the use of lymphoid effector cells. Of the other probably even more important host defense system against tumor growth, the mono-nuclear phagocyte system, only monocytes (mo) have been reinfused which, however, represent immature precursor cells and acquire full functional competence ...


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