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Differential regulation of proinflammatory and hematopoietic cytokines in human macrophages after infection with human immunodeficiency virus

Esser, R. ; Glienke, W. ; von Briesen, H. ; Rübsamen-Waigmann, H. ; Andreesen, Reinhard



Abstract

Cells of the macrophage lineage (MAC) play an important role in human immunodeficiency virus (HIV) infection. However, the knowledge on the extent of macrophage involvement in the pathogenesis of HIV infection is still incomplete. In this study we examined the secretory repertoire of HIV-infected MAC with respect to the proinflammatory cytokines tumor necrosis factor-alpha (TNF-alpha), ...

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