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Characterization of cells prepared by dendritic cell-tumor cell fusion

Gottfried, Eva ; Krieg, René ; Eichelberg, Christian ; Andreesen, Reinhard ; Mackensen, Andreas ; Krause, Stefan W



Abstract

Dendritic cells (DCs) are professional antigen-presenting cells currently being discussed as a potent tool for antitumor vaccination strategies. The approach consisting of the in vitro generation of DC-tumor cell hybrids may be advantageous for individualized vaccines since there is no need for the determination of MHC-restricted tumor-associated antigens recognized by T cells. As recent ...

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