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Fischer, Karin ; Hoffmann, Petra ; Voelkl, Simon ; Meidenbauer, Norbert ; Ammer, Julia ; Edinger, Matthias ; Gottfried, Eva ; Schwarz, Sabine ; Rothe, Gregor ; Hoves, Sabine ; Renner, Kathrin ; Timischl, Birgit ; Mackensen, Andreas ; Kunz-Schughart, Leoni ; Andreesen, Reinhard ; Krause, Stefan W. ; Kreutz, Marina

Inhibitory effect of tumor cell-derived lactic acid on human T cells

Article

Fischer, Karin, Hoffmann, Petra, Voelkl, Simon, Meidenbauer, Norbert, Ammer, Julia, Edinger, Matthias , Gottfried, Eva, Schwarz, Sabine, Rothe, Gregor, Hoves, Sabine , Renner, Kathrin, Timischl, Birgit, Mackensen, Andreas, Kunz-Schughart, Leoni, Andreesen, Reinhard, Krause, Stefan W. and Kreutz, Marina (2007) Inhibitory effect of tumor cell-derived lactic acid on human T cells. Blood 109 (9), pp. 3812-9.



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Details

Item typeArticle
Journal or Publication TitleBlood
PublisherAMER SOC HEMATOLOGY
Place of PublicationWASHINGTON
Volume109
Number of Issue or Book Chapter9
Page Rangepp. 3812-9
Date2007
Date of publication20 Apr 2010 09:34
InstitutionsMedicine > Institut für Funktionelle Genomik > Lehrstuhl für Funktionelle Genomik (Prof. Oefner)
Medicine > Lehrstuhl für Innere Medizin III (Hämatologie und Internistische Onkologie)
Medicine > Lehrstuhl für Pathologie
Identification Number
ValueType
17255361PubMed ID
10.1182/blood-2006-07-035972DOI
Classification
NotationType
Biological Transport/immunologyMESH
Cell Cycle Proteins/immunologyMESH
Cell Proliferation/drug effectsMESH
Dose-Response Relationship, DrugMESH
FemaleMESH
Glycolysis/immunologyMESH
HumansMESH
Lactic Acid/pharmacologyMESH
Lymphocyte Activation/immunologyMESH
MaleMESH
Neoplasms/pathologyMESH
Oncogene Proteins/immunologyMESH
Spheroids, CellularMESH
T-Lymphocytes/pathologyMESH
Tumor Cells, CulturedMESH
KeywordsHIGH LACTATE LEVELS; MELANOMA PATIENTS; CAPILLARY-ELECTROPHORESIS; AEROBIC GLYCOLYSIS; EXTRACELLULAR PH; ACTIVATION; HYPOXIA; EXPRESSION; CANCERS; TARGET;
Dewey Decimal Classification600 Technology > 610 Medical sciences Medicine
StatusPublished
RefereedYes, this version has been refereed
Created at the University of RegensburgYes
Item ID14499

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