Jakse, G. ; Hofstädter, Ferdinand ; Engelmann, U. ; Jacobi, G. H.
Alternative Links zum Volltext:DOI
| Dokumentenart: | Artikel |
|---|
| Titel eines Journals oder einer Zeitschrift: | World Journal of Urology = World J Urol |
|---|
| Verlag: | Springer |
|---|
| Band: | 1 |
|---|
| Seitenbereich: | S. 82-85 |
|---|
| Datum: | 1983 |
|---|
| Institutionen: | Medizin > Lehrstuhl für Pathologie |
|---|
| Identifikationsnummer: | | Wert | Typ |
|---|
| 10.1007/BF00326748 | DOI |
|
|---|
| Dewey-Dezimal-Klassifikation: | 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin |
|---|
| Status: | Veröffentlicht |
|---|
| Begutachtet: | Unbekannt / Keine Angabe |
|---|
| An der Universität Regensburg entstanden: | Unbekannt / Keine Angabe |
|---|
| Dokumenten-ID: | 15062 |
|---|
Zusammenfassung
Topical chemoprophylaxis with adriamycin
was administered to 49 patients with UICC-stages pTA
and PT1 (pathological stage 0 and A) of transitional cell
carcinoma of the urinary bladder. Tumor specimens obtained
prior to initiation of the instillation protocol were
evaluated with regard to ABH-antigenicity. ABH-antigens
were present in tumors of 19 patients and none of
these developed ...
Zusammenfassung
Topical chemoprophylaxis with adriamycin
was administered to 49 patients with UICC-stages pTA
and PT1 (pathological stage 0 and A) of transitional cell
carcinoma of the urinary bladder. Tumor specimens obtained
prior to initiation of the instillation protocol were
evaluated with regard to ABH-antigenicity. ABH-antigens
were present in tumors of 19 patients and none of
these developed muscle-infiltrating recurrences during
or after intravesical chemoprophylaxis. The primary
lesions of 30 patients were deleted of antigens; only 5
(16%) developed a progressive recurrence. Compared to
a historical control group this is thought to be a true reduction
of invasive tumor recurrences in ABH-negative
tumors by adriamycin. We herein propose that ABHantigenicity
may serve as a valuable prescreening indicator
for or against topical chemoprophylaxis.
Altmetric