Seidl, M. ; Steinbach, P. ; Wörle, K. ; Hofstädter, Ferdinand
Alternative Links zum Volltext:Pubmed
Dokumentenart: | Artikel |
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Titel eines Journals oder einer Zeitschrift: | Ultrasonics |
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Verlag: | Elsevier |
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Band: | 32 |
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Nummer des Zeitschriftenheftes oder des Kapitels: | 5 |
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Seitenbereich: | S. 397-400 |
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Datum: | 1994 |
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Institutionen: | Medizin > Lehrstuhl für Pathologie |
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Identifikationsnummer: | |
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Klassifikation: | Notation | Art |
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Basement Membrane/pathology | MESH | Endothelium, Vascular/ultrastructure | MESH | Extracellular Space/physiology | MESH | Female | MESH | Humans | MESH | Microscopy, Electron, Scanning | MESH | Ultrasonics/adverse effects | MESH | Umbilical Veins/ultrastructure | MESH |
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Dewey-Dezimal-Klassifikation: | 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin |
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Status: | Veröffentlicht |
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Begutachtet: | Unbekannt / Keine Angabe |
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An der Universität Regensburg entstanden: | Unbekannt / Keine Angabe |
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Dokumenten-ID: | 15288 |
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Zusammenfassung
Human umbilical cords were exposed to high amplitude focussed ultrasonic pulses with focal energy densities 0.6 and 0.4 mJ mm-2. The endothelium of the exposed vessel (vein) was examined by means of confocal laser scanning microscopy and scanning electron microscopy. The degree of tissue change ranged from the induction of stress fibres and intercellular gaps to the complete detachment of ...
Zusammenfassung
Human umbilical cords were exposed to high amplitude focussed ultrasonic pulses with focal energy densities 0.6 and 0.4 mJ mm-2. The endothelium of the exposed vessel (vein) was examined by means of confocal laser scanning microscopy and scanning electron microscopy. The degree of tissue change ranged from the induction of stress fibres and intercellular gaps to the complete detachment of endothelial cells combined with damage of the basement membrane. An increased number of stress fibres may indicate an increased vessel wall permeability. This might explain the enhanced effects in experimental tumour therapy that have been found by other authors when combining shock-waves with drugs.