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Blood group phenotype determines lectin-mediated adhesion of Pseudomonas aeruginosa to human outer ear canal epithelium

Steuer, M. K. ; Beuth, J. ; Hofstädter, Ferdinand ; Pröbster, L. ; Ko, H. L. ; Pulverer, G. ; Strutz, J.



Abstract

Pseudomonas aeruginosa is the most frequent bacterial pathogen causing acute diffuse otitis externa. In a recent prospective phase II study we demonstrated that lectin-mediated bacterial adhesion can be blocked by receptor-analogue carbohydrates in patients suffering from Pseudomonas aeruginosa-induced acute otitis externa. In this investigation, human ABO blood group antigens were analysed on ...

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