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- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-156576
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.15657
Alternative Links zum Volltext:Pubmed
Zusammenfassung
Soluble guanylyl cyclase (sGC) is one of the key enzymes of the nitric-oxide (NO)/cyclic 3',5'-guanosine monophosphate (cGMP) pathway. Located in virtually all mammalian cells, it controls the vessel tone, smooth muscle cell growth, platelet aggregation, and leukocyte adhesion. In vivo sGC activity is mainly regulated by NO which in turn is released from L-arginine by nitric oxide synthases. One ...
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