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Dithranol, Glucose-6-phosphate Dehydrogenase Inhibition and Active Oxygen Species

Müller, K., Seidel, M., Braun, C., Ziereis, K. and Wiegrebe, Wolfgang (1991) Dithranol, Glucose-6-phosphate Dehydrogenase Inhibition and Active Oxygen Species. Arzneimittel-Forschung 41 (11), pp. 1176-1181.

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Date of publication of this fulltext: 12 Jul 2010 05:14


Inhibition of glucose-6-phosphate dehydrogenase (G6- PDH) by dithranpl (anthralin, CAS 480-22-8) has been studied in the presence of catalase, superoxide dismutase (SOD) and various scavengers of active oxygen species. Most scavengers were found to be either inhibitors of G6- PDH by themselves or simply without effect. The combined addition of catalase and SOD as well as the heatdenatured enzymes ...


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Item type:Article
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Alumni or Retired Professors > Prof. Wiegrebe
Keywords:Anthralin, in vitro studies • Antipsoriatic drugs • CAS 480-22-8 • Dithranol • Free radicals • Glucose-6-phosphate dehydrogenase, inhibition
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:15735
Owner only: item control page


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