Alkaloids of Cynanchum vincetoxicum: Efficacy against MDA-MB-231 Mammary Carcinoma Cells

URN to cite this document:: urn:nbn:de:bvb:355-epub-157796
DOI to cite this document:: 10.5283/epub.15779

Tanner, U. ; Wiegrebe, Wolfgang

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Date of publication of this fulltext: 12 Jul 2010 07:49

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Item type:	Article
Journal or Publication Title:	Archiv der Pharmazie
Publisher:	John Wiley & Sons
Volume:	326
Page Range:	pp. 67-72
Date:	1993
Institutions:	Chemistry and Pharmacy > Institute of Pharmacy > Alumni or Retired Professors > Prof. Wiegrebe
Dewey Decimal Classification:	500 Science > 540 Chemistry & allied sciences
Status:	Published
Refereed:	Yes, this version has been refereed
Created at the University of Regensburg:	Unknown
Item ID:	15779

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Abstract

Alkaloids 1-4 from Cynanchum vincetoxicum (asclepiadaceae) (Scheme 1) do not have affinity to the oestrogen receptor but they inhibit the growth of the hormone-independent mammary carcinoma cells MDA-MB-231 (Fig. 1) and bind to nucleosides and nucleotides (Table 1). Intercalation was not observed. Die Alkaloide 1-4 aus Cynanchum vincetoxicum (Asclepiadaceae) (Scheme 1) zeigen keine Affinität zum ...

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