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O-Methylating Enzymes of Dopamine and Dopamine Derived Tetrahydroisoquinoline, Salsolinol

Iwasa, K., Kamigauchi, M., Saiki, K., Takao, N. and Wiegrebe, Wolfgang (1993) O-Methylating Enzymes of Dopamine and Dopamine Derived Tetrahydroisoquinoline, Salsolinol. Phytochemistry 32, pp. 1443-1448.

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Date of publication of this fulltext: 12 Jul 2010 07:52


By using an LC/API-MS system, it was demonstrated that dopamine condenses with acetaldehyde to give salsolinol which is further metabolized to produce 6-O-methylsalsolinol (isosalsoline) which is O- and N-methylated to provide salsolidine and N-methylisosalsoline, respectively, in several plant tissue cultures of Papaveraceae. Almost none of the 3-O-methoxytyramine formed from dopamine was ...


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Item type:Article
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Alumni or Retired Professors > Prof. Wiegrebe
Keywords:Corydalis pallida var. tenuis, C. ochotensis var. raddeana, C. incisa; Macleaya cordata; Papaveraceae; Cynanchum vincetoxicum; Asclepiadaceae; dopamine; isoquinoline alkaloids; tissue cultures; metabolism
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:15782
Owner only: item control page


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