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DNA-Interaction, Estrogen Receptor Affinity, and Cytostatic Activity of 1,3-Diphenylpropane-1,3-diamine-Pt(II) Complexes

Kammermeier, T. and Wiegrebe, Wolfgang (1995) DNA-Interaction, Estrogen Receptor Affinity, and Cytostatic Activity of 1,3-Diphenylpropane-1,3-diamine-Pt(II) Complexes. Archiv der Pharmazie 328 (5), pp. 409-415.

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Abstract

The Pt(II) complexes of 1,3-diphenylpropane-1,3-diamines (part IV 2)) were tested for DNA interaction (UV-difference spectroscopy, Tables 1 and 2), for affinity to the estrogen receptor (calf uterus cytosol; scarcely any affinity), and for cytostatic activity at estrogen independent MDA-MB 231 cells (Tables 3 and 4) and estrogen dependent MCF-7 cells (Tables 5 and 6). The data are compared with ...

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Item type:Article
Date:1995
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Alumni or Retired Professors > Prof. Wiegrebe
Interdisciplinary Subject Network:Not selected
Identification Number:
ValueType
10.1002/ardp.19953280504DOI
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:15905
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