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Characterization of r-protein variants in Saccharomyces cerevisiae

Neueder, Andreas (2011) Characterization of r-protein variants in Saccharomyces cerevisiae. PhD, Universität Regensburg.

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Date of publication of this fulltext: 05 Jul 2011 06:56

Abstract (English)

Single ribosomal proteins are required for specific steps in eukaryotic ribosome biogenesis. Consequently, depletion of a certain r-protein leads to a block or delay in pre-rRNA maturation and/or transport of precursor subunits. However, the exact molecular functions of the r-proteins in these processes are still obscure. To accurately investigate the molecular functions and to determine possible ...

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Translation of the abstract (German)

Einzelne ribosomale Proteine werden für spezifische Schritte in der Ribosomen Biogenese von Eukaryonten benötigt. Demzufolge führt das Fehlen eines bestimmten ribosomalen Proteins zur Verzögerung bzw. Verhinderung von Vorläufer rRNA Reifungschritten und/oder dem Transport von Vorläufer Partikeln. Bis jetzt sind die genauen molekularen Funktionen der ribosomalen Proteine jedoch noch größtenteils ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:5 July 2011
Referee:Prof. Dr. Herbert Tschochner and Prof. Dr. Reinhard Sterner
Date of exam:1 July 2010
Institutions:Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Biochemie III > Prof. Dr. Herbert Tschochner
Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Biochemie III > Dr. Philipp Milkereit
Interdisciplinary Subject Network:Not selected
Keywords:ribosome, ribosomal proteins, biogenesis, molecular function, rRNA processing, structure, export, mutant analysis
Dewey Decimal Classification:500 Science > 570 Life sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:15928
Owner only: item control page

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