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- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-159621
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.15962
Alternative Links zum Volltext:Pubmed
Zusammenfassung
Chemotaxis by a macrophage cell line, RAW264, is specifically inhibited by the intracellular accumulation of 3-deazaadenosylhomocysteine (3-deaza-AdoHcy). Intracellular accumulation of 3-deaza-AdoHcy is the result of incubation of the cells with 3-deazaadenosine, a compound that can function both as a substrate and as an inhibitor of adenosylhomocysteine (AdoHcy) hydrolase. Accumulation of AdoHcy ...
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