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- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-159966
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.15996
Zusammenfassung
We investigated the role of cytokines for the growth of CD4-8-thymocytes (double negative thymocytes) (DNT) in vitro and found that IL-1-induced IL-2-dependent proliferation of only the IL-2R-positive DNT subpopulation. The presence of IL-1 during the first 18 h of culture was sufficient for an optimal response and suggested that IL-1 induced DNT differentiation. We could indeed show by RNA dot ...
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