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In vitro and in vivo characterization of alginate based anisotropic capillary hydrogels to guide directed axon regeneration

Pawar, Kiran Chandrakantrao (2011) In vitro and in vivo characterization of alginate based anisotropic capillary hydrogels to guide directed axon regeneration. PhD, Universität Regensburg.

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Date of publication of this fulltext: 17 Jan 2011 14:46

Abstract (English)

Functional recovery of injured nerves depends on longitudinally directed regrowth of axons over the site of injury, which requires a regrowth directing structured scaffold. In the present study we used alginate-based anisotropic hydrogels, which contain linearly aligned capillaries with variable diameters as a guiding structure for oriented nerve regeneration. These gels were formed by a ...

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Translation of the abstract (German)

Die funktionelle Wiederherstellung verletzter Nerven hängt unter anderem von einem longitudinal gerichteten Wachstum von Axonen über den Ort der Verletzung hinweg ab, wofür eine physikalische Leitstruktur benötigt wird. In der vorliegenden Arbeit wurden Alginat-basierte anisotrope Hydrogele, die parallel zueinander orientierte Kapillaren aufweisen, als Leitstruktur für eine orientierte ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:17 January 2011
Referee:PD Dr. Rainer Mueller and Prof. Dr. Norbert Weidner and Prof. Dr. Achim Goepferich
Date of exam:20 September 2010
Institutions:Chemistry and Pharmacy > Institut für Physikalische und Theoretische Chemie > Chair of Chemistry VI - Physical Chemistry (Solution Chemistry) > Prof. Dr. Werner Kunz
Interdisciplinary Subject Network:Not selected
Keywords:Nerve regeneration, axon outgrowth, glial cells, alginate, gelatin, hydrogel, anisotropy, Nervenregeneration, Axonaussprossung, Gliazellen, Alginat, Gelatine, Hydrogel, Anisotropie
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:16238
Owner only: item control page

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