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Endogenous interferon specifically regulates Newcastle disease virus-induced cytokine gene expression in mouse macrophages

Zawatzky, R., Wurmbaeck, H., Falk, Werner and Homfeld, A. (1991) Endogenous interferon specifically regulates Newcastle disease virus-induced cytokine gene expression in mouse macrophages. Journal of virology 65 (9), pp. 4839-4846.

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Abstract

In macrophages from inbred mice, the magnitude of the interferon (IFN) response to Newcastle disease virus (NDV) infection is under genetic control of the If-1 locus, which carries the allele for either high (h) or low (l) IFN production. Here, we report that the activity of genes within the If-1 locus is influenced by macrophage-derived endogenous IFN. In addition to various other biological ...

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Item type:Article
Date:1991
Institutions:Medicine > Lehrstuhl für Innere Medizin I
Identification Number:
ValueType
2542574PubMed ID
Classification:
NotationType
2',5'-Oligoadenylate Synthetase/biosynthesisMESH
AnimalsMESH
Blotting, NorthernMESH
Cell DivisionMESH
Cell LineMESH
Cytokines/geneticsMESH
Enzyme InductionMESH
Gene ExpressionMESH
Interferons/physiologyMESH
Macrophage Colony-Stimulating Factor/pharmacologyMESH
Macrophages/physiologyMESH
MaleMESH
MiceMESH
Mice, Inbred StrainsMESH
Newcastle disease virus/immunologyMESH
Vesicular stomatitis Indiana virus/geneticsMESH
Virus ReplicationMESH
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:16489
Owner only: item control page

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