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Lipid profiling of FPLC-separated lipoprotein fractions by electrospray ionization tandem mass spectrometry

Wiesner, Philipp (2010) Lipid profiling of FPLC-separated lipoprotein fractions by electrospray ionization tandem mass spectrometry. PhD, Universität Regensburg.

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Date of publication of this fulltext: 11 Oct 2010 09:42

Abstract (English)

Glycerophospholipid and sphingolipid species and their bioactive metabolites are important regulators of lipoprotein and cell function. Aim of the study was to develop a method for lipid species profiling of separated lipoprotein classes. Methods: Human serum lipoproteins VLDL, LDL and HDL of 21 healthy fasting blood donors were separated by fast performance liquid chromatography (FPLC) from 50 ...


Translation of the abstract (German)

Cholesterin, Glycerophospho- und Sphingolipide und deren aktive Metaboliten sind wichtige Komponenten und Regulatoren des Lipoprotein- und Zellstoffwechsels. Phosphatidylcholin und Sphingomyelin dienen als Vorläufer der Verbindungen Lysophospatidylcholine bzw. Ceramide und regulieren darüber hinaus zentrale Schritte des Lipoproteinstoffwechsels. Neben der direkten Wirkung dieser Lipide auf den ...


Export bibliographical data

Item type:Thesis of the University of Regensburg (PhD)
Date:11 October 2010
Referee:Prof. Dr. Gerd Schmitz and PD Dr. Christa Büchler
Date of exam:14 September 2010
Institutions:Medicine > Lehrstuhl für Klinische Chemie und Laboratoriumsmedizin
Interdisciplinary Subject Network:Not selected
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:16550
Owner only: item control page


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