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Solution structures of the inactive and BeF₃-activated response regulator CheY2

Riepl, Hubert ; Scharf, Birgit ; Schmitt, Rüdiger ; Kalbitzer, Hans Robert ; Maurer, Till



Abstract

The chemotactic signalling chain to the flagellar motor of Sinorhizobium meliloti features a new type of response regulator, CheY2. CheY2 activated by phosphorylation (CheY2-P) controls the rotary speed of the flagellar motor (instead of reversing the sense of rotation), and it is efficiently dephosphorylated by phospho-retrotransfer to the cognate kinase, CheA. Here, we report the NMR solution ...

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