Go to content
UR Home

Antifungal, antiprotozoal, cytotoxic and piscicidal properties of justicidin B and a new arylnaphthalide lignan from Phyllanthus piscatorum

Gertsch, Juerg ; Tobler, Rebekka Thoeni ; Brun, Reto ; Sticher, Otto ; Heilmann, Jörg



Abstract

Using activity against Candida albicans as a lead, the bioactivity-guided fractionation of the CH2Cl2 ext. of P. piscatorum led to the isolation of the arylnaphthalide lignan justicidin B (I), which was found to be present in high amts., and a new C-11 hydroxylated deriv. that we named piscatorin (II). We provide evidence that I is the main active principle of P. piscatorum, showing the same ...

plus


Owner only: item control page
  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de

Dissertations: dissertationen@ur.de

Research data: daten@ur.de

Contact persons