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| Dokumentenart: | Artikel | ||||
|---|---|---|---|---|---|
| Titel eines Journals oder einer Zeitschrift: | Revista latinoamericana de química | ||||
| Verlag: | Monterrey | ||||
| Band: | 32 | ||||
| Nummer des Zeitschriftenheftes oder des Kapitels: | 3 | ||||
| Seitenbereich: | S. 87-94 | ||||
| Datum: | 2004 | ||||
| Zusätzliche Informationen (Öffentlich): | CAN 142:403366 1-1 Pharmacology 38681-23-1P Role: NPO (Natural product occurrence), PUR (Purification or recovery), THU (Therapeutic use), BIOL (Biological study), OCCU (Occurrence), PREP (Preparation), USES (Uses) (butein from mosquitoxylum jamaicense ext. showed strongest cytotoxic activity than 2,3-trans-3-methoxyfustin in KB cell line); 83-46-5P (beta -Sitosterol); 99-24-1P (Methyl gallate); 480-18-2P ((+)-Taxifolin); 514-47-6P (Euphol); 444573-46-0P Role: NPO (Natural product occurrence), PUR (Purification or recovery), THU (Therapeutic use), BIOL (Biological study), OCCU (Occurrence), PREP (Preparation), USES (Uses) (butein from mosquitoxylum jamaicense ext. showed strongest cytotoxic activity than Me gallate in KB cell line); 14351-29-2P (Dammarenediol II) Role: NPO (Natural product occurrence), PUR (Purification or recovery), THU (Therapeutic use), BIOL (Biological study), OCCU (Occurrence), PREP (Preparation), USES (Uses) (butein from mosquitoxylum jamaicense ext. showed strongest cytotoxic activity than dammarenediol in KB cell line); 487-52-5P (Butein) Role: NPO (Natural product occurrence), PUR (Purification or recovery), THU (Therapeutic use), BIOL (Biological study), OCCU (Occurrence), PREP (Preparation), USES (Uses) (butein from mosquitoxylum jamaicense ext. showed strongest cytotoxic activity than dammarenediol, 2,3-trans-3-methoxyfustin, Me gallate, sulfuretin in KB cell line); 120-05-8P (Sulfuretin) Role: NPO (Natural product occurrence), PUR (Purification or recovery), THU (Therapeutic use), BIOL (Biological study), OCCU (Occurrence), PREP (Preparation), USES (Uses) (butein from mosquitoxylum jamaicense ext. showed strongest cytotoxic activity than sulfuretin in KB cell line) | ||||
| Institutionen: | Chemie und Pharmazie > Institut für Pharmazie > Lehrstuhl Pharmazeutische Biologie (Prof. Heilmann) | ||||
| Identifikationsnummer: |
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| Stichwörter / Keywords: | Anacardiaceae Cytotoxicity Mass spectra (butein from mosquitoxylum jamaicense ext. showed strongest cytotoxic activity than dammarenediol, 2,3-trans-3-methoxyfustin, Me gallate, sulfuretin in KB cell line) Natural products Role: NPO (Natural product occurrence), PUR (Purification or recovery), THU (Therapeutic use), BIOL (Biological study), OCCU (Occurrence), PREP (Preparation), USES (Uses) (butein from mosquitoxylum jamaicense ext. showed strongest cytot NMR (carbon-13 butein from mosquitoxylum jamaicense ext. showed strongest cytotoxic activity than dammarenediol, 2,3-trans-3-methoxyfustin, Me gallate, sulfuretin in KB cell line) mosquitoxylum jamaicense ext cytotoxicity | ||||
| Dewey-Dezimal-Klassifikation: | 500 Naturwissenschaften und Mathematik > 570 Biowissenschaften, Biologie 500 Naturwissenschaften und Mathematik > 540 Chemie | ||||
| Status: | Veröffentlicht | ||||
| Begutachtet: | Ja, diese Version wurde begutachtet | ||||
| An der Universität Regensburg entstanden: | Nein | ||||
| Dokumenten-ID: | 17221 |
Zusammenfassung
In the traditional medicine of the Sierra Popoluca (Veracruz, Mexico) a decoction of the bark of Mosquitoxylum jamaicense (Anacardiaceae) is used to treat menstrual problems and gonorrhea. Both, the non-polar as well as the polar ext. showed significant cytotoxicity against KB cells in vitro. The fractionation and isolation process resulted in non-cytotoxic trans-anacardic acid, a new but ...
Zusammenfassung
In the traditional medicine of the Sierra Popoluca (Veracruz, Mexico) a decoction of the bark of Mosquitoxylum jamaicense (Anacardiaceae) is used to treat menstrual problems and gonorrhea. Both, the non-polar as well as the polar ext. showed significant cytotoxicity against KB cells in vitro. The fractionation and isolation process resulted in non-cytotoxic trans-anacardic acid, a new but probably not genuine compd. Furthermore, we report for the first time on the cytotoxicity of the isolated and previously known compds. dammarenediol, 2,3-trans-3-methoxyfustin and sulfuretin.
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