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[7-fluoro-4-chromone-3-sulfur compounds]

Lowe, W. ; Elz, Sigurd ; Reiser, H. ; Schott, S.



Abstract

The novel 7-fluoro-4-chromone-3-sulfur compounds 5-12 were synthesized from the sulfinic acid 4, which can be obtained from the enaminone 3 and thionyl chloride. Especially the Flosequinane-like sulfoxide 12 was prepared and the vasodilating activity was evaluated in isolated ring segments of rat aorta.


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