Model evaluation for glycolytic oscillations in yeast biotransformations of xenobiotics

URN to cite this document:: urn:nbn:de:bvb:355-epub-17346

Brusch, Lutz ; Cuniberti, Gianaurelio ; Bertau, Martin

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Date of publication of this fulltext: 05 Aug 2009 13:31

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Abstract

Anaerobic glycolysis in yeast perturbed by the reduction of xenobiotic ketones is studied numerically in two models which possess the same topology but different levels of complexity. By comparing both models' predictions for concentrations and fluxes as well as steady or oscillatory temporal behavior we answer the question what phenomena require what kind of minimum model abstraction. While mean ...