Schneider, M. R., Schönenberger, Helmut, Michel, R. T. und Fortmeyer, H. P. (1982) Synthesis and evaluation of catechol analogs of diethylstilbestrol on a hormone-dependent human mammary carcinoma implanted in nude mice. Journal of cancer research and clinical oncology 104 (3), S. 219-227.
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Zusammenfassung
E-3,4-bis(3',4'-diacetoxyphenyl)hex-3-ene (I) [84675-77-4], E-4(4'-acetoxyphenyl)-3(3',4'-diacetoxyphenyl)hex-3-ene (II) [84675-78-5], and E-4(3'-acetoxyphenyl)-3(3',4'-diacetoxyphenyl)hex-3-ene (III) [84675-79-6] were synthesized by known methods and were tested for biol. effects with respect to their estradiol receptor affinity, uterotropic and antiuterotropic properties, and antitumor ...
Bibliographische Daten exportieren
| Dokumentenart: | Artikel | ||||
|---|---|---|---|---|---|
| Datum: | 1982 | ||||
| Zusätzliche Informationen (Öffentlich): | CAN 98:119855 2-4 Mammalian Hormones 91-16-7 Role: RCT (Reactant), RACT (Reactant or reagent) (acylation of); 4927-54-2P; 4927-55-3P; 84675-71-8P Role: RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (prepn. and alkylation of); 56-53-1DP; 84675-77-4P; 84675-78-5P; 84675-79-6P Role: BAC (Biological activity or effector, except adverse), BSU (Biological study, unclassified), SPN (Synthetic preparation), BIOL (Biological study), PREP (Preparation) (prepn. and biol. activity of); 75513-68-7P; 84675-75-2P; 84675-76-3P Role: RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (prepn. and ether cleavage and acetylation of); 84675-72-9P; 84675-73-0P; 84675-74-1P Role: RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (prepn. and reaction with Et magnesium bromide and dehydration of); 50-28-2 Role: BIOL (Biological study) (receptor binding of, DES catechol analogs interaction in) | ||||
| Institutionen: | Chemie und Pharmazie > Institut für Pharmazie > Entpflichtete oder im Ruhestand befindliche Professoren > Prof. Schönenberger | ||||
| Projekte: | SFB 234 | ||||
| Identifikationsnummer: |
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| Stichwörter / Keywords: | Neoplasm inhibitors (DES catechol analogs) Uterus (DES catechol analogs effect on growth of) Receptors Role: BIOL (Biological study) (estradiol binding by, DES catechol analog interaction in) Carcinoma (of mammary gland, DES catechol analogs inhibition of) Mammary gland (neoplasm, carcinoma, DES catechol analogs inhibition of) DES catechol analog prepn estrogen carcinoma mammary inhibition DES analog uterus growth DES catechol analog | ||||
| Dewey-Dezimal-Klassifikation: | 500 Naturwissenschaften und Mathematik > 540 Chemie | ||||
| Status: | Veröffentlicht | ||||
| Begutachtet: | Ja, diese Version wurde begutachtet | ||||
| An der Universität Regensburg entstanden: | Ja | ||||
| Eingebracht am: | 12 Nov 2010 09:21 | ||||
| Zuletzt geändert: | 08 Mrz 2017 08:28 | ||||
| Dokumenten-ID: | 17635 |
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