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Mammary tumor inhibiting effect of 3,3'-diacetoxy-alpha ,beta -dialkylstilbenes and of related stilbene oxides

Schneider, Martin R. ; Schönenberger, Helmut ; Michel, Ralf T. ; Fortmeyer, H. P.



Abstract

3,3'-Diacetoxy-alpha ,beta -dialkylstilbenes (C1-4 alkyl), 3,3'-dihydroxy-alpha ,beta -diethylstilbene (I) [80149-87-7], and their corresponding stilbene oxides were synthesized. These compds. competitively antagonized in vitro the interaction of 3H-labeled estradiol [50-28-2] with its receptor. 3,3'-diacetoxy-alpha ,beta -diethylstilbene [80149-84-4], 3,3'-diacetoxy-alpha ,beta -diethylstilbene ...

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