Go to content
UR Home

Studies on the mechanism activity of cis-bis(glycylglycine ethyl ester)platinum(II) chloride - action on nucleic acid metabolism

Seidenberger, Horst ; Schönenberger, Helmut ; Beck, Wolfgang ; Girnth-Weller, Michael ; Lux, Franz ; Zeisler, Rolf



Abstract

cis-bis(glycylglycinethylester)platinum II chloride (I) [60426-60-0] interfered with the nucleic acid metab. in tumor cells by inhibiting the DNA template activity as well as the DNA- [9012-90-2] and RNA polymerase [9014-24-8] and the ribonucleotide reductase [9040-57-7] system. The activity of I was similar to the therapeutically used Pt coordination complex cis-Pt(NH3)2Cl2.


Owner only: item control page
  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de

Dissertations: dissertationen@ur.de

Research data: daten@ur.de

Contact persons