Go to content
UR Home

Relations between structure and antitumor activity of cis-dichloro[bis(oligopeptide ester)platinum(II)] complexes

Seidenberger, Horst ; Wappes, Beate ; Schönenberger, Helmut ; Beck, Wolfgang ; Girnth-Weller, Michael ; Ruckdeschel, Gotthart


Several title compds., cis- and trans-[PtA2X2] complexes (A = esters of oligopeptides; X = Cl, oxalate, or malonate), were tested for their ability to inhibit thymidine 3H incorporation by suspensions by ADJ/PC6 plasmacytoma cells, as an index of antitumor action. The effect was markedly dependent on the type, no., and sequence of the amino acids in the peptide component. The most active compd. ...


Owner only: item control page
  1. Homepage UR

University Library

Publication Server


Publishing: oa@ur.de
0941 943 -4239 or -69394

Dissertations: dissertationen@ur.de
0941 943 -3904

Research data: datahub@ur.de
0941 943 -5707

Contact persons