Ring-substituted 1,2-dialkylated 1,2-bis(hydroxyphenyl)ethanes. 2. Synthesis and estrogen receptor binding affinity of 4,4'-, 5,5'-, and 6,6'-disubstituted metahexestrols
Hartmann, Rolf W., Heindl, Alexander und Schönenberger, Helmut (1984) Ring-substituted 1,2-dialkylated 1,2-bis(hydroxyphenyl)ethanes. 2. Synthesis and estrogen receptor binding affinity of 4,4'-, 5,5'-, and 6,6'-disubstituted metahexestrols. Journal of medicinal chemistry 27 (5), S. 577-585.Veröffentlichungsdatum dieses Volltextes: 12 Nov 2010 09:02
Artikel
Alternative Links zum Volltext
Beteiligte Einrichtungen
Details
| Dokumentenart | Artikel | ||||
| Titel eines Journals oder einer Zeitschrift | Journal of medicinal chemistry | ||||
| Verlag: | American Chemical Society | ||||
|---|---|---|---|---|---|
| Band: | 27 | ||||
| Nummer des Zeitschriftenheftes oder des Kapitels: | 5 | ||||
| Seitenbereich: | S. 577-585 | ||||
| Datum | 1984 | ||||
| Zusätzliche Informationen (Öffentlich) | CAN 100:156305 25-7 Benzene, Its Derivatives, and Condensed Benzenoid Compounds 71953-69-0 Role: RCT (Reactant), RACT (Reactant or reagent) (Friedel-Crafts acetylation of); 33719-74-3 Role: RCT (Reactant), RACT (Reactant or reagent) (Grignard carboxylation of); 82846-18-2 Role: RCT (Reactant), RACT (Reactant or reagent) (acid chloride prepn. from); 102-50-1 Role: RCT (Reactant), RACT (Reactant or reagent) (diazotization and fluorination of); 71953-72-5 Role: RCT (Reactant), RACT (Reactant or reagent) (estrogenic and antiestrogenic activity of); 367-83-9P; 578-39-2P; 82846-19-3P; 89106-53-6P Role: RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (prepn. and Grignard ethylation of); 52238-48-9P Role: SPN (Synthetic preparation), PREP (Preparation) (prepn. and alkali fusion of); 89106-15-0P; 89106-19-4P; 89106-20-7P; 89106-21-8P; 89106-23-0P; 89106-25-2P; 89106-26-3P; 89106-27-4P; 89106-29-6P; 89106-30-9P; 89106-32-1P; 89106-34-3P; 89106-37-6P; 89106-40-1P Role: SPN (Synthetic preparation), PREP (Preparation) (prepn. and estrogen receptor binding activity of); 89106-12-7P; 89106-22-9P; 89106-28-5P; 89106-43-4P; 89106-47-8P; 89106-50-3P Role: SPN (Synthetic preparation), PREP (Preparation) (prepn. and estrogenic and antiestrogenic activity of); 71953-69-0P; 89106-13-8P; 89106-16-1P; 89106-33-2P; 89106-35-4P; 89106-38-7P; 89106-41-2P; 89106-44-5P; 89106-48-9P; 89106-51-4P Role: SPN (Synthetic preparation), PREP (Preparation) (prepn. and ether cleavage of); 89106-31-0P Role: RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (prepn. and hydrazine redn. of); 76473-05-7P; 89106-14-9P; 89106-17-2P; 89106-36-5P; 89106-45-6P Role: RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (prepn. and hydrogenation of); 2338-54-7P Role: RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (prepn. and oxidn. of); 29578-81-2P; 37951-49-8P; 41497-31-8P; 82846-20-6P; 89106-18-3P; 89106-39-8P; 89106-42-3P; 89106-46-7P; 89106-49-0P; 89106-52-5P; 89121-16-4P Role: RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (prepn. and reductive self-coupling of); 82477-67-6P Role: SPN (Synthetic preparation), PREP (Preparation) (prepn. of, and acid chloride prepn. from); 89106-54-7P Role: SPN (Synthetic preparation), PREP (Preparation) (prepn. of, and sodium salt prepn. from); 89106-24-1P Role: RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (prepn., sapon., and alkylation of); 118-90-1 Role: RCT (Reactant), RACT (Reactant or reagent) (sulfonation of) | ||||
| Institutionen | Chemie und Pharmazie > Institut für Pharmazie > Entpflichtete oder im Ruhestand befindliche Professoren > Prof. Schönenberger | ||||
| Identifikationsnummer |
| ||||
| Stichwörter / Keywords | Estrogens Role: RCT (Reactant), RACT (Reactant or reagent) (and inhibitors, metahexestrol derivs.) Molecular structure-biological activity relationship (antiestrogenic, of metahexestrol derivs.) Molecular structure-biological activity relationship (estrogenic, of metahexestrol derivs.) Coupling reaction (reductive, of phenylpropanols and propiophenones, mesohexestrol derivs. by) metahexestrol deriv prepn estrogen antiestrogen hexanediol diphenyl deriv | ||||
| Dewey-Dezimal-Klassifikation | 500 Naturwissenschaften und Mathematik > 540 Chemie | ||||
| Status | Veröffentlicht | ||||
| Begutachtet | Ja, diese Version wurde begutachtet | ||||
| An der Universität Regensburg entstanden | Ja | ||||
| Dokumenten-ID | 17646 |
Bibliographische Daten exportieren
Nur für Besitzer und Autoren: Kontrollseite des Eintrags
Altmetric
Altmetric