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Selective prostatic tumor inhibiting effect of an endocrine-active platinum complex

Schneider, M. R., Spruss, Thilo, Schiller, C. D., Humm, A. and Schönenberger, Helmut (1988) Selective prostatic tumor inhibiting effect of an endocrine-active platinum complex. Progress in cancer research and therapy 35 (Horm.), pp. 509-513.

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In rats, the Pt complex I inhibited prostate and mammary gland hormone-dependent tumors, but had no effect on any of the hormone-independent tumors tested. The prostatic tumor-inhibiting activity of I was better than that of the related ligand without Pt. The endocrine effects of I on accessory sex organ wt. and testosterone levels were only slightly less than those of the potent estrogen ...


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Item type:Article
Additional Information (public):CAN 110:376 1-6 Pharmacology 58-22-0 (Testosterone) Role: BIOL (Biological study) (endocrine-active platinum complex effect on, of blood, prostatic tumor inhibition in relation to); 117773-99-6 Role: BIOL (Biological study) (hormone-dependent prostate carcinoma inhibition by)
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Alumni or Retired Professors > Prof. Schönenberger
Projects:SFB 234
Identification Number:
Keywords:Neoplasm inhibitors (carcinoma, endocrine-active platinum complex as, against hormone-dependent mammary and prostate gland cells) Reproductive organ (male accessory, endocrine-active platinum complex effect on, prostatic tumor inhibition in relation to) Prostate gland (neoplasm, carcinoma, inhibition of hormone-dependent, by endocrine-active platinum complex) Mammary gland (neoplasm, carcinoma, hormone-dependent, inhibition of, by endocrine-active platinum complex) hormone dependent prostate tumor platinum complex endocrine active platinum complex prostate tumor mammary tumor endocrine active platinum complex
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:17671
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