Go to content
UR Home

Diamine ligand release from the cisplatin analog [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]dichloroplatinum(II) in cell culture medium

Bednarski, Patrick J. ; Truembach, Barbara ; Kratochwil, Nicole A. ; Schönenberger, Helmut



Abstract

The stability of the five-membered chelate ring of the cisplatin analog [meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]dichloroplatinum(II) (I) was investigated under typical cell culture conditions (IMEM-Richter's medium with 10% fetal calf serum, 37 Deg). The platinum compd. was radiolabeled with tritium in the meta position of the arom. ring by an acid-catalyzed tritium-exchange ...

plus


Owner only: item control page
  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de

Dissertations: dissertationen@ur.de

Research data: daten@ur.de

Contact persons