Investigation of the Configurational and Conformational Influences on the Hormonal Activity of 1,2-Bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamines and of their Platinum(II) Complexes. 1. Synthesis, Estradiol Receptor Affinity, and Estrogenic Activity of Diastereomeric [N-Alkyl- and N,N'-Dialkyl-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]dichloroplatinum(II) Complexes
Gust, Ronald, Niebler, Karlheinz und Schönenberger, Helmut (1995) Investigation of the Configurational and Conformational Influences on the Hormonal Activity of 1,2-Bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamines and of their Platinum(II) Complexes. 1. Synthesis, Estradiol Receptor Affinity, and Estrogenic Activity of Diastereomeric [N-Alkyl- and N,N'-Dialkyl-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]dichloroplatinum(II) Complexes. Journal of Medicinal Chemistry 38 (12), S. 2070-2079.Veröffentlichungsdatum dieses Volltextes: 10 Nov 2010 11:58
Artikel
Alternative Links zum Volltext
Beteiligte Einrichtungen
Details
| Dokumentenart | Artikel | ||||
| Titel eines Journals oder einer Zeitschrift | Journal of Medicinal Chemistry | ||||
| Verlag: | American Chemical Society | ||||
|---|---|---|---|---|---|
| Band: | 38 | ||||
| Nummer des Zeitschriftenheftes oder des Kapitels: | 12 | ||||
| Seitenbereich: | S. 2070-2079 | ||||
| Datum | 1995 | ||||
| Zusätzliche Informationen (Öffentlich) | CAN 123:46660 78-7 Inorganic Chemicals and Reactions 10025-99-7 (Potassium tetrachloroplatinate(2-); 83363-98-8; 164411-34-1 Role: RCT (Reactant), RACT (Reactant or reagent) (for prepn. of platinum(II) chloro bis(dichlorohydroxyphenyl)ethylenediamine complex); 164411-32-9P; 164411-33-0P Role: RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (for prepn. of platinum(II) chloro bis(dichlorohydroxyphenyl)ethylenediamine complex); 105856-23-3; 105928-14-1; 111086-58-9; 111112-21-1 Role: BAC (Biological activity or effector, except adverse), BSU (Biological study, unclassified), BIOL (Biological study) (prepn., estradiol receptor affinity, and estrogenic activity of diastereomeric platinum(II) chloro bis(dichlorohydroxyphenyl)ethylenediamine complexes); 82772-86-9P; 82772-87-0P; 82772-89-2P; 82772-90-5P; 164411-30-7P; 164411-31-8P Role: BAC (Biological activity or effector, except adverse), BSU (Biological study, unclassified), RCT (Reactant), SPN (Synthetic preparation), BIOL (Biological study), PREP (Preparation), RACT (Reactant or reagent) (prepn., estradiol receptor affinity, and estrogenic activity of diastereomeric platinum(II) chloro bis(dichlorohydroxyphenyl)ethylenediamine complexes); 164411-28-3P; 164411-29-4P; 164577-11-1P; 164577-12-2P; 164577-13-3P; 164577-14-4P Role: BAC (Biological activity or effector, except adverse), BSU (Biological study, unclassified), SPN (Synthetic preparation), BIOL (Biological study), PREP (Preparation) (prepn., estradiol receptor affinity, and estrogenic activity of diastereomeric platinum(II) chloro bis(dichlorohydroxyphenyl)ethylenediamine complexes) | ||||
| Institutionen | Chemie und Pharmazie > Institut für Pharmazie > Entpflichtete oder im Ruhestand befindliche Professoren > Prof. Schönenberger | ||||
| Identifikationsnummer |
| ||||
| Stichwörter / Keywords | Configuration Conformation and Conformers (prepn., estradiol receptor affinity, and estrogenic activity of diastereomeric platinum(II) chloro bis(dichlorohydroxyphenyl)ethylenediamine complexes) Estrogens Role: BAC (Biological activity or effector, except adverse), BSU (Biological study, unclassified), BIOL (Biological study) (prepn., estradiol receptor affinity, and estrogenic activity of diastereomeric platinum(II) chloro bis(dichlorohydroxyp Estrogen receptors Role: BSU (Biological study, unclassified), BIOL (Biological study) (prepn., estradiol receptor affinity, and estrogenic activity of diastereomeric platinum(II) chloro bis(dichlorohydroxyphenyl)ethylenediamine complexes) Receptors Role: BSU (Biological study, unclassified), BIOL (Biological study) (estrogen, prepn., estradiol receptor affinity, and estrogenic activity of diastereomeric platinum(II) chloro bis(dichlorohydroxyphenyl)ethylenediamine complexes) Molecular structure-biological activity relationship (estrogen receptor-binding, prepn., estradiol receptor affinity, and estrogenic activity of diastereomeric platinum(II) chloro bis(dichlorohydroxyphenyl)ethylenediamine complexes) platinum chloro hydroxyphenylethylenediamine estrogen receptor binding ethylenediamine deriv platinum complex estrogen activity | ||||
| Dewey-Dezimal-Klassifikation | 500 Naturwissenschaften und Mathematik > 540 Chemie | ||||
| Status | Veröffentlicht | ||||
| Begutachtet | Ja, diese Version wurde begutachtet | ||||
| An der Universität Regensburg entstanden | Ja | ||||
| Dokumenten-ID | 17707 |
Bibliographische Daten exportieren
Nur für Besitzer und Autoren: Kontrollseite des Eintrags
Altmetric
Altmetric