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(1,2-Diphenylethylenediamine)-platinum(II) complex compounds

Schönenberger, Helmut ; Wappes, Beate ; Jennerwein, Margaretha ; Von Angerer, Erwin ; Engel, Juergen


The prepn. of antitumor pharmaceuticals contg. (1,2-diphenylethylenediamine) Pt(II)-complexes I (where R1, R2, R3, R4, same or different, are: H, OH, C1-6 alkoxy, substituted C2-6 alkanoyloxy or C3-6 alkenoxyloxy, of which at least one R group is not H; X = physiol. tolerable anion) is given. Thus, (+)-dichloro-[1,2-bis-(4-hydroxyphenyl)ethylenediamine]platinum(II) (II) [91326-62-4], dissolved in ...


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