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Chemical constitution and bacteriostatic activity of isomeric hydroxybenzamides. II. Antimycotic substances

Schönenberger, Helmut, Holzheu-Eckardt, Juergen, Bamann, Eugen and Mehnert, Brigitte (1963) Chemical constitution and bacteriostatic activity of isomeric hydroxybenzamides. II. Antimycotic substances. Arzneimittel-Forschung = Drug research 13, pp. 936-939.

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cf. CA 59, 2070e. Of the hydroxybenzamides tested, the o-hydroxybenzanilides with 1 or 2 halogen atoms in the anilide ring exhibit the highest activity against Staphylococcus aureus. Highest activity was shown by the 4-bromoanilide and 2,4-dichloroanilide. The fact that the phenolic hydroxyl group has a marked influence on bacteriostatic properties was demonstrated by complete loss of such ...


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Item type:Article
Additional Information (public):CAN 60:92729 62 Microbial Biochemistry 614-17-5; 14180-11-1; 14216-34-3; 90887-50-6 (Derived from data in the 7th Collective Formula Index (1962-1966); 55-21-0 (Benzamide); 87-17-2 (Salicylanilide); 89-55-4 (Salicylic acid, 5-bromo-); 613-93-4 (Benzamide, N-methyl-); 619-57-8 (Benzamide, p-hydroxy-); 1697-18-3 (Salicylanilide, 2'-chloro-); 2280-99-1 (p-Anisamide, N-butyl-); 2627-77-2 (Salicylanilide, 4'-bromo-); 3400-22-4 (p-Anisamide, N-methyl-); 3679-63-8 (Salicylanilide, 4'-chloro-); 3679-68-3 (Benzanilide, 4'-chloro-4-hydroxy-); 6137-53-7 (Salicylanilide, 2',5'-dichloro-); 7403-41-0 (p-Anisamide, N-ethyl-); 7464-43-9 (p-Anisamide, N-propyl-); 7464-44-0 (p-Anisamide, N-isopropyl-); 7465-88-5 (p-Anisanilide); 7595-61-1 (p-Anisanilide, 4'-chloro-); 10546-70-0 (Benzamide, N-propyl-); 13410-91-8 (Salicylanilide, 2',3'-dichloro-); 14121-97-2 (Benzanilide, 4-hydroxy-); 24448-71-3 (Salicylanilide, 3'-chloro-); 27519-68-2 (Benzamide, p-hydroxy-N-propyl-); 27522-79-8 (Benzamide, N-ethyl-p-hydroxy-); 27559-45-1 (Benzanilide, 3-hydroxy-); 36965-04-5 (Benzanilide, 4'-chloro-4-hydroxy-, acetate); 37183-28-1 (Salicylanilide, 2',4'-dichloro-); 39114-64-2 (Benzamide, N-cyclohexyl-p-hydroxy-); 52189-56-7 (Benzanilide, 4'-bromo-4-hydroxy-); 58748-19-9 (Benzamide, ethoxy-); 60696-49-3 (Benzamide, N-butyl-p-hydroxy-); 62639-20-7 (Benzanilide, 2'-chloro-4-hydroxy-); 73544-81-7 (Benzanilide, 3'-chloro-3-hydroxy-); 73544-82-8 (Benzanilide, 4'-chloro-3-hydroxy-); 83191-67-7 (Benzamide, p-hydroxy-N-isopropyl-); 92044-46-7 (Benzanilide, 2'-chloro-3-hydroxy-); 92044-47-8 (Benzanilide, 3'-chloro-4-hydroxy-); 92433-68-6 (Benzanilide, 2'-chloro-4-hydroxy-, acetate); 92433-69-7 (Benzanilide, 3'-chloro-4-hydroxy-, acetate); 92433-81-3 (Carbonic acid, methyl ester, ester with 2'-chloro-4-hydroxybenzanilide); 92433-81-3 (Benzanilide, 2'-chloro-4-hydroxy-, methyl carbonate); 92433-82-4 (Benzanilide, 4'-chloro-4-hydroxy-, methyl carbonate); 92433-82-4 (Carbonic acid, methyl ester, ester with 4'-chloro-4-hydroxybenzanilide); 92905-58-3 (Benzanilide, 4'-bromo-3-hydroxy-); 97027-63-9 (Benzanilide, 2',3'-dichloro-3-hydroxy-); 97027-64-0 (Benzanilide, 2',4'-dichloro-3-hydroxy-); 97027-66-2 (Benzanilide, 2',5'-dichloro-3-hydroxy-) (bactericidal action of)
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Alumni or Retired Professors > Prof. Schönenberger
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Keywords:Bactericides, Disinfectants and Antiseptics (hydroxybenzamide derivs. as) Staphylococcus (aureus (includes albus and citreus), hydroxybenzamide deriv. effect on) Benzoic acid Benzoic acid Salicylic acid (bactericidal action of)
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:18165
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